[C-11]NPA PET-amphetamine in Cocaine Use Disorders
Status:
Recruiting
Trial end date:
2028-09-01
Target enrollment:
Participant gender:
Summary
This study uses [11C]NPA positron emission tomography (PET) and a d-amphetamine challenge to
image amphetamine induced dopamine release in the striatum in subjects with cocaine use
disorders (CUD). Amphetamine-induced dopamine release data from this study will be correlated
with [11C]NOP-1A VT measured at baseline in the midbrain. [11C]NOP-1A PET data will be used
from aim 1 (see, Study Record: Imaging CRF X NOP interactions in Cocaine Use Disorders)